CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family tRNA-splicing endonuclease

Enzyme Information

4.6.1.16
tRNA-intron lyase.
based on mapping to UniProt Q8TGZ7
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.

UniProtKB Entries (1)

Q8TGZ7
ENDA_METKA
Methanopyrus kandleri AV19
TRNA-splicing endonuclease

PDB Structure

PDB 5X89
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity
Kaneta, A., Fujishima, K., Morikazu, W., Hori, H., Hirata, A.
Nucleic Acids Res.