CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Adenine phosphoribosyltransferase

Enzyme Information

2.4.2.7
Adenine phosphoribosyltransferase.
based on mapping to UniProt P49435
AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- 5-amino-4-imidazolecarboxamide can replace adenine.

UniProtKB Entries (1)

P49435
APT1_YEAST
Saccharomyces cerevisiae S288C
Adenine phosphoribosyltransferase 1

PDB Structure

PDB 5VJP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase.
Harris, L.D., Harijan, R.K., Ducati, R.G., Evans, G.B., Hirsch, B.M., Schramm, V.L.
ACS Chem. Biol.