CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.20 | 5' to 3' exonuclease, C-terminal subdomain |
Domain Context
CATH Clusters
| Superfamily | 5' to 3' exonuclease, C-terminal subdomain |
| Functional Family | exonuclease 1 |
Enzyme Information
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt Q9UQ84
|
UniProtKB Entries (1)
| Q9UQ84 |
EXO1_HUMAN
Homo sapiens
Exonuclease 1
|
PDB Structure
| PDB | 5V0E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I.
Proc. Natl. Acad. Sci. U.S.A.
|