CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Protein tyrosine phosphatase type IVA 3

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt O75365
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q8NE01
CNNM3_HUMAN
Homo sapiens
Metal transporter CNNM3

PDB Structure

PDB 5TSR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Zhang, H., Kozlov, G., Li, X., Wu, H., Gulerez, I., Gehring, K.
Sci Rep