CATH Classification

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Alkaline phosphatase PafA

Enzyme Information

3.1.3.1
Alkaline phosphatase.
based on mapping to UniProt Q9KJX5
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).

UniProtKB Entries (1)

Q9KJX5
ALPH_ELIME
Elizabethkingia meningoseptica
Alkaline phosphatase PafA

PDB Structure

PDB 5TOO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution.
Sunden, F., AlSadhan, I., Lyubimov, A., Doukov, T., Swan, J., Herschlag, D.
J. Biol. Chem.