CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Histone acetyltransferase p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q09472
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-
Transferring groups other than amino-acyl groups.
based on mapping to UniProt Q09472

UniProtKB Entries (1)

Q09472
EP300_HUMAN
Homo sapiens
Histone acetyltransferase p300

PDB Structure

PDB 5NU5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles.
Hugle, M., Lucas, X., Ostrovskyi, D., Regenass, P., Gerhardt, S., Einsle, O., Hau, M., Jung, M., Breit, B., Gunther, S., Wohlwend, D.
Angew. Chem. Int. Ed. Engl.