1 keywords

CATH Domain 5n2oA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.150 DNA polymerase; domain 1
Homologous Superfamily 1.10.150.50 Transcription Factor, Ets-1

Domain Context

CATH Clusters

Superfamily Transcription Factor, Ets-1
Functional Family Tumor protein 63 (p63)

Enzyme Information

UniProtKB Entries (1)

O88898
P63_MOUSE
Mus musculus
Tumor protein 63

PDB Structure

PDB 5N2O
External Links
Method SOLUTION NMR
Organism
Primary Citation
Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.
Russo, C., Osterburg, C., Sirico, A., Antonini, D., Ambrosio, R., Wurz, J.M., Rinnenthal, J., Ferniani, M., Kehrloesser, S., Schafer, B., Guntert, P., Sinha, S., Dotsch, V., Missero, C.
Proc. Natl. Acad. Sci. U.S.A.