CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family protein tyrosine phosphatase type IVA 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q63739
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q63739
TP4A1_MOUSE
Mus musculus
Protein tyrosine phosphatase type IVA 1

PDB Structure

PDB 5MMZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
Gimenez-Mascarell, P., Oyenarte, I., Hardy, S., Breiderhoff, T., Stuiver, M., Kostantin, E., Diercks, T., Pey, A.L., Ereno-Orbea, J., Martinez-Chantar, M.L., Khalaf-Nazzal, R., Claverie-Martin, F., Muller, D., Tremblay, M.L., Martinez-Cruz, L.A.
J. Biol. Chem.