CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Purine nucleoside phosphorylase DeoD-type

Enzyme Information

2.4.2.1
Purine-nucleoside phosphorylase.
based on mapping to UniProt P0ABP8
(1) Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. (2) Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.
-!- Specificity not completely determined. -!- Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5.

UniProtKB Entries (1)

P0ABP8
DEOD_ECOLI
Escherichia coli K-12
Purine nucleoside phosphorylase DeoD-type

PDB Structure

PDB 5IU6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7-deazahypoxanthine.
Timofeev, V.I., Zhukhlistova, N.E., Abramchik, Y.A., Fateev, I.I., Kostromina, M.A., Muravieva, T.I., Esipov, R.S., Kuranova, I.P.
Acta Crystallogr F Struct Biol Commun