CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2000 | Glycogen Phosphorylase B; |
Domain Context
CATH Clusters
| Superfamily | Glycogen Phosphorylase B; |
| Functional Family | Trehalose-6-phosphate synthase |
Enzyme Information
| 2.4.1.15 |
Alpha,alpha-trehalose-phosphate synthase (UDP-forming).
based on mapping to UniProt Q92410
UDP-alpha-D-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
-!- See also EC 2.4.1.36.
|
UniProtKB Entries (1)
| Q92410 |
TPS1_CANAL
Candida albicans SC5314
Alpha,alpha-trehalose-phosphate synthase [UDP-forming]
|
PDB Structure
| PDB | 5HVL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio
|