CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family Glycerol kinase

Enzyme Information

2.7.1.30
Glycerol kinase.
based on mapping to UniProt D3KVM3
ATP + glycerol = ADP + sn-glycerol 3-phosphate.
-!- Glycerone and L-glyceraldehyde can act as acceptors. -!- UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors.

UniProtKB Entries (1)

D3KVM3
D3KVM3_TRYBG
Trypanosoma brucei gambiense
Glycerol kinase

PDB Structure

PDB 5GN6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase ofTrypanosoma brucei brucei.
Balogun, E.O., Inaoka, D.K., Shiba, T., Tsuge, C., May, B., Sato, T., Kido, Y., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Watanabe, Y.I., Moore, A.L., Harada, S., Kita, K.
Faseb J.