CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1250.10
Functional Family Interleukin-6

Enzyme Information

UniProtKB Entries (1)

P05231
IL6_HUMAN
Homo sapiens
Interleukin-6

PDB Structure

PDB 5FUC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.
Adams, R., Burnley, R.J., Valenzano, C.R., Qureshi, O., Doyle, C., Lumb, S., Del Carmen Lopez, M., Griffin, R., McMillan, D., Taylor, R.D., Meier, C., Mori, P., Griffin, L.M., Wernery, U., Kinne, J., Rapecki, S., Baker, T.S., Lawson, A.D., Wright, M., Ettorre, A.
Sci Rep