CATH Classification

Domain Context

CATH Clusters

Superfamily Fructose-1,6-Bisphosphatase, subunit A, domain 1
Functional Family SAL1 phosphatase

Enzyme Information

3.1.3.7
3'(2'),5'-bisphosphate nucleotidase.
based on mapping to UniProt Q42546
Adenosine 3',5'-bisphosphate + H(2)O = adenosine 5'-phosphate + phosphate.
-!- Also acts on 3'-phosphoadenylylsulfate, and on the corresponding 2'-phosphates.
3.1.3.57
Inositol-1,4-bisphosphate 1-phosphatase.
based on mapping to UniProt Q42546
1D-myo-inositol 1,4-bisphosphate + H(2)O = 1D-myo-inositol 4-phosphate + phosphate.
-!- Acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar V(max) for both substrates, but with a 5 times higher affinity for the bisphosphate. -!- Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.

UniProtKB Entries (1)

Q42546
DPNP1_ARATH
Arabidopsis thaliana
SAL1 phosphatase

PDB Structure

PDB 5ESY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase.
Chan, K.X., Mabbitt, P.D., Phua, S.Y., Mueller, J.W., Nisar, N., Gigolashvili, T., Stroeher, E., Grassl, J., Arlt, W., Estavillo, G.M., Jackson, C.J., Pogson, B.J.
Proc.Natl.Acad.Sci.USA