CATH Classification

Domain Context

CATH Clusters

Superfamily Plasminogen Kringle 4
Functional Family Hepatocyte growth factor

Enzyme Information

UniProtKB Entries (1)

P14210
HGF_HUMAN
Homo sapiens
Hepatocyte growth factor

PDB Structure

PDB 5CT3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Exploring the chemical space of the lysine-binding pocket of the first kringle domain of hepatocyte growth factor/scatter factor (HGF/SF) yields a new class of inhibitors of HGF/SF-MET binding.
Sigurdardottir, A.G., Winter, A., Sobkowicz, A., Fragai, M., Chirgadze, D., Ascher, D.B., Blundell, T.L., Gherardi, E.
Chem Sci