CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.25 | Alpha Horseshoe |
|
1.25.50 | Zincin-like fold |
|
1.25.50.20 |
Domain Context
CATH Clusters
| Superfamily | 1.25.50.20 |
| Functional Family | Leucyl-cystinyl aminopeptidase |
Enzyme Information
| 3.4.11.3 |
Cystinyl aminopeptidase.
based on mapping to UniProt Q9UIQ6
Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half- cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however.
-!- Belongs to peptidase family M1.
|
UniProtKB Entries (1)
| Q9UIQ6 |
LCAP_HUMAN
Homo sapiens
Leucyl-cystinyl aminopeptidase
|
PDB Structure
| PDB | 5C97 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing.
J Immunol.
|