CATH Classification

Domain Context

CATH Clusters

Superfamily L-arginine/glycine Amidinotransferase; Chain A
Functional Family Protein-arginine deiminase type-2

Enzyme Information

3.5.3.15
Protein-arginine deiminase.
based on mapping to UniProt Q9Y2J8
Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
-!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.

UniProtKB Entries (1)

Q9Y2J8
PADI2_HUMAN
Homo sapiens
Protein-arginine deiminase type-2

PDB Structure

PDB 4N2N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Slade, D.J., Fang, P., Dreyton, C.J., Zhang, Y., Fuhrmann, J., Rempel, D., Bax, B.D., Coonrod, S.A., Lewis, H.D., Guo, M., Gross, M.L., Thompson, P.R.
Acs Chem.Biol.