CATH Domain 4l7uA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.142	Poly(ADP-ribose) Polymerase; domain 1
	1.20.142.10	Poly(ADP-ribose) polymerase, regulatory domain

Domain Context

CATH Clusters

Superfamily	Poly(ADP-ribose) polymerase, regulatory domain
Functional Family	Poly [ADP-ribose] polymerase

Enzyme Information

2.4.2.-

Pentosyltransferases.

based on mapping to UniProt Q9Y6F1

UniProtKB Entries (1)

PARP3_HUMAN

Homo sapiens

Protein mono-ADP-ribosyltransferase PARP3

PDB Structure

PDB	4L7U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3. Lindgren, A.E., Karlberg, T., Ekblad, T., Spjut, S., Thorsell, A.G., Andersson, C.D., Nhan, T.T., Hellsten, V., Weigelt, J., Linusson, A., Schuler, H., Elofsson, M. J.Med.Chem.