CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.640 | Aspartate Aminotransferase; domain 2 | |
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Functional Family | Cystathionine gamma-synthase homolog |
Enzyme Information
2.5.1.48 |
Cystathionine gamma-synthase.
based on mapping to UniProt P56069
O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate.
-!- Also reacts with H(2)S and methanethiol as replacing agents, producing homocysteine and methionine, respectively. -!- In the absence of thiol, can also catalyze beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia. -!- Formerly EC 4.2.99.9.
|
UniProtKB Entries (1)
P56069 |
METB_HELPY
Helicobacter pylori 26695
Cystathionine gamma-synthase
|
PDB Structure
PDB | 4L0O |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure determination of cystathionine gamma-synthase from Helicobacter pylori
To be Published
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