CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Titin a

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8WZ42
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q8WZ42
TITIN_HUMAN
Homo sapiens
Titin

PDB Structure

PDB 4JNW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line.
Bogomolovas, J., Gasch, A., Simkovic, F., Rigden, D.J., Labeit, S., Mayans, O.
Open Biol