CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P51812
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P51812
KS6A3_HUMAN
Homo sapiens
Ribosomal protein S6 kinase alpha-3

PDB Structure

PDB 4JG8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Electrophilic fragment-based design of reversible covalent kinase inhibitors.
Miller, R.M., Paavilainen, V.O., Krishnan, S., Serafimova, I.M., Taunton, J.
J.Am.Chem.Soc.