CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.35
3-hydroxyacyl-CoA dehydrogenase.
based on mapping to UniProt P34439
(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
-!- Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate. -!- Some enzymes act, more slowly, with NADP(+). -!- Broad specificity to acyl chain-length (cf. EC 1.1.1.211).

UniProtKB Entries (1)

P34439
HCDH1_CAEEL
Caenorhabditis elegans
Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1

PDB Structure

PDB 4J0F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Purification, crystallization and preliminary crystallographic analysis of 3-hydroxyacyl-CoA dehydrogenase from Caenorhabditis elegans.
Xu, Y., Sun, F.
Acta Crystallogr.,Sect.F