CATH Classification

Domain Context

CATH Clusters

Superfamily Hypothetical oxidoreductase yiak; domain 2
Functional Family Ureidoglycolate dehydrogenase

Enzyme Information

1.1.1.350
Ureidoglycolate dehydrogenase (NAD(+)).
based on mapping to UniProt P77555
(S)-ureidoglycolate + NAD(+) = N-carbamoyl-2-oxoglycine + NADH.
-!- Involved in catabolism of purines. -!- The enzyme from the bacterium Escherichia coli is specific for NAD(+). -!- Cf. EC 1.1.1.154.

UniProtKB Entries (1)

P77555
ALLD_ECOLI
Escherichia coli K-12
Ureidoglycolate dehydrogenase (NAD(+))

PDB Structure

PDB 4H8A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
Kim, M.I., Shin, I., Cho, S., Lee, J., Rhee, S.
Plos One