CATH Classification

Domain Context

CATH Clusters

Superfamily Nitrogenase molybdenum iron protein domain
Functional Family Histidinol dehydrogenase

Enzyme Information

1.1.1.23
Histidinol dehydrogenase.
based on mapping to UniProt Q8G2R2
L-histidinol + H(2)O + 2 NAD(+) = L-histidine + 2 NADH.
-!- Also oxidizes L-histidinal. -!- The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31.

UniProtKB Entries (1)

Q8G2R2
HISX_BRUSU
Brucella suis 1330
Histidinol dehydrogenase

PDB Structure

PDB 4G09
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis.
D'ambrosio, K., Lopez, M., Dathan, N.A., Ouahrani-Bettache, S., Kohler, S., Ascione, G., Monti, S.M., Winum, J.Y., De Simone, G.
Biochimie