CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.605 | Aldehyde Dehydrogenase; Chain A, domain 1 | |
3.40.605.10 | Aldehyde Dehydrogenase; Chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | Aldehyde Dehydrogenase; Chain A, domain 1 |
Functional Family | Aldehyde dehydrogenase, mitochondrial |
Enzyme Information
1.2.1.3 |
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt P05091
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.
|
UniProtKB Entries (1)
P05091 |
ALDH2_HUMAN
Homo sapiens
Aldehyde dehydrogenase, mitochondrial
|
PDB Structure
PDB | 4FR8 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Vascular Bioactivation of Nitroglycerin by Aldehyde Dehydrogenase-2: REACTION INTERMEDIATES REVEALED BY CRYSTALLOGRAPHY AND MASS SPECTROMETRY.
J.Biol.Chem.
|