CATH Classification

Domain Context

CATH Clusters

Superfamily Plasminogen Kringle 4
Functional Family Plasminogen

Enzyme Information

3.4.21.7
Plasmin.
based on mapping to UniProt P00747
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
-!- Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.14.

UniProtKB Entries (1)

P00747
PLMN_HUMAN
Homo sapiens
Plasminogen

PDB Structure

PDB 4DUR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The X-ray crystal structure of full-length human plasminogen
Law, R.H.P., Caradoc-Davies, T., Cowieson, N., Horvath, A.J., Quek, A.J., Encarnacao, J.A., Steer, D., Cowan, A., Zhang, Q., Lu, B.G.C., Pike, R.N., Smith, A.I., Coughlin, P.B., Whisstock, J.C.
Cell Rep