CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Ribosomal RNA large subunit methyltransferase J

Enzyme Information

2.1.1.266
23S rRNA (adenine(2030)-N(6))-methyltransferase.
based on mapping to UniProt P37634
S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L- homocysteine + N(6)-methyladenine(2030) in 23S rRNA.
-!- The recombinant RlmJ protein is most active in methylating deproteinized 23S ribosomal subunit, and does not methylate the completely assembled 50S subunits.

UniProtKB Entries (1)

P37634
RLMJ_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase J

PDB Structure

PDB 4BLV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Punekar, A.S., Liljeruhm, J., Shepherd, T.R., Forster, A.C., Selmer, M.
Nucleic Acids Res.