CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Probable serine/threonine-protein kinase nek1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q96PY6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q96PY6
NEK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase Nek1

PDB Structure

PDB 4B9D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Nima-Related Kinase 1 (Nek1) with Inhibitor.
Elkins, J.M., Hanchuk, T.D.M., Lovato, D.V., Basei, F.L., Meirelles, G.V., Kobarg, J., Szklarz, M., Vollmar, M., Mahajan, P., Rellos, P., Zhang, Y., Krojer, T., Pike, A.C.W., Canning, P., von Delft, F., Raynor, J., Bountra, C., Arrowsmith, C., Edwards, A., Knapp, S.
To be Published