CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.320 | Lambda Exonuclease; Chain A | |
3.90.320.10 |
Domain Context
CATH Clusters
Superfamily | 3.90.320.10 |
Functional Family |
Enzyme Information
3.1.11.3 |
Exodeoxyribonuclease (lambda-induced).
based on mapping to UniProt P03697
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
|
UniProtKB Entries (1)
P03697 |
EXO_LAMBD
Escherichia virus Lambda
Exonuclease
|
PDB Structure
PDB | 3SLP |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Proc.Natl.Acad.Sci.USA
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