CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family receptor-type tyrosine-protein phosphatase zeta isoform X1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P23471
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P23471
PTPRZ_HUMAN
Homo sapiens
Receptor-type tyrosine-protein phosphatase zeta

PDB Structure

PDB 3S97
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A complex between contactin-1 and the protein tyrosine phosphatase PTPRZ controls the development of oligodendrocyte precursor cells.
Lamprianou, S., Chatzopoulou, E., Thomas, J.L., Bouyain, S., Harroch, S.
Proc.Natl.Acad.Sci.USA