1 keywords

CATH Domain 3s8sA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.330 RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily 3.30.70.330
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt O15047
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

O15047
SET1A_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD1A

PDB Structure

PDB 3S8S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the RRM domain of human SETD1A
Chao, X., Tempel, W., Bian, C., Cerovina, T., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J.
to be published