CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.465.10
Functional Family Cytokinin dehydrogenase 1

Enzyme Information
Cytokinin dehydrogenase.
based on mapping to UniProt Q9T0N8
N(6)-dimethylallyladenine + acceptor + H(2)O = adenine + 3-methylbut-2- enal + reduced acceptor.
-!- Converts zeatin and related cytokinins. -!- Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is a dimethylallyl or other prenyl group. -!- Although this activity was previously thought to be catalyzed by a hydrogen-peroxide-forming oxidase, this enzyme does not require oxygen for activity and does not form hydrogen peroxide. -!- 2,6-dichloroindophenol, methylene blue, nitroblue tetrazolium, phenazine methosulfate and Cu(2+) in the presence of imidazole can act as acceptors.

UniProtKB Entries (1)

Zea mays
Cytokinin dehydrogenase 1

PDB Structure

External Links
Primary Citation
Kinetic and structural investigation of the cytokinin oxidase/dehydrogenase active site.
Kopecny, D., Koncitikova, R., Popelka, H., Briozzo, P., Vigouroux, A., Kopecna, M., Zalabak, D., Sebela, M., Skopalova, J., Frebort, I., Morera, S.
Febs J.