CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.390 | Enolase-like; domain 1 | |
3.30.390.30 | FAD/NAD-linked reductase, C-terminal dimerisation domain |
Domain Context
CATH Clusters
Superfamily | 3.30.390.30 |
Functional Family | Thioredoxin reductase 1, cytoplasmic |
Enzyme Information
1.8.1.9 |
Thioredoxin-disulfide reductase.
based on mapping to UniProt Q16881
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.
|
UniProtKB Entries (1)
Q16881 |
TRXR1_HUMAN
Homo sapiens
Thioredoxin reductase 1, cytoplasmic
|
PDB Structure
PDB | 3QFB |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of the human thioredoxin reductase-thioredoxin complex
Nat Commun
|