CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P35030
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P35030
TRY3_HUMAN
Homo sapiens
Trypsin-3

PDB Structure

PDB 3L3T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin.
Salameh, M.A., Soares, A.S., Navaneetham, D., Sinha, D., Walsh, P.N., Radisky, E.S.
J.Biol.Chem.