CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.81
Hydroxypyruvate reductase.
based on mapping to UniProt Q8ZQ30
D-glycerate + NAD(P)(+) = hydroxypyruvate + NAD(P)H.
1.1.1.79
Glyoxylate reductase (NADP(+)).
based on mapping to UniProt Q8ZQ30
Glycolate + NADP(+) = glyoxylate + NADPH.
-!- Also reduces hydroxypyruvate to glycerate. -!- Has some affinity for NAD(+).

UniProtKB Entries (1)

Q8ZQ30
GHRA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Glyoxylate/hydroxypyruvate reductase A

PDB Structure

PDB 3KBO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.14 Angstrom Crystal Structure of Putative Oxidoreductase (ycdW) from Salmonella typhimurium in Complex with NADP.
Minasov, G., Wawrzak, Z., Skarina, T., Onopriyenko, O., Papazisi, L., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published