CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family Spermidine N(1)-acetyltransferase

Enzyme Information

2.3.1.57
Diamine N-acetyltransferase.
based on mapping to UniProt Q9HL57
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.

UniProtKB Entries (1)

Q9HL57
PAIA_THEAC
Thermoplasma acidophilum DSM 1728
Spermidine N(1)-acetyltransferase

PDB Structure

PDB 3K9U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production.
Filippova, E.V., Shuvalova, L., Minasov, G., Kiryukhina, O., Zhang, Y., Clancy, S., Radhakrishnan, I., Joachimiak, A., Anderson, W.F.
Proteins