1 keywords

CATH Domain 3k2iB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family acyl-coenzyme A thioesterase 4

Enzyme Information

3.1.2.2
Palmitoyl-CoA hydrolase.
based on mapping to UniProt Q8N9L9
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.
3.1.2.3
Succinyl-CoA hydrolase.
based on mapping to UniProt Q8N9L9
Succinyl-CoA + H(2)O = CoA + succinate.

UniProtKB Entries (1)

Q8N9L9
ACOT4_HUMAN
Homo sapiens
Peroxisomal succinyl-coenzyme A thioesterase

PDB Structure

PDB 3K2I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human Acyl-coenzyme A thioesterase 4
Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H.
To be Published