CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Aminopeptidase, subunit E, domain 1
Functional Family Core histone macro-H2A

Enzyme Information

UniProtKB Entries (1)

O75367
H2AY_HUMAN
Homo sapiens
Core histone macro-H2A.1

PDB Structure

PDB 3IIF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
Timinszky, G., Till, S., Hassa, P.O., Hothorn, M., Kustatscher, G., Nijmeijer, B., Colombelli, J., Altmeyer, M., Stelzer, E.H., Scheffzek, K., Hottiger, M.O., Ladurner, A.G.
Nat.Struct.Mol.Biol.