1 keywords

CATH Domain 3ihyA01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.25 Alpha Horseshoe
Topology 1.25.40 Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homologous Superfamily 1.25.40.70 Phosphatidylinositol 3-kinase, accessory domain (PIK)

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase, accessory domain (PIK)
Functional Family

Enzyme Information

2.7.1.137
Phosphatidylinositol 3-kinase.
based on mapping to UniProt Q8NEB9
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo- inositol 3-phosphate.

UniProtKB Entries (1)

Q8NEB9
PK3C3_HUMAN
Homo sapiens
Phosphatidylinositol 3-kinase catalytic subunit type 3

PDB Structure

PDB 3IHY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human PIK3C3 crystal structure
Siponen, M.I., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Kragh Nielsen, T., Moche, M., Nyman, T., Persson, C., Roos, A.K., Sagemark, J., Schueler, H., Schutz, P., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P.
TO BE PUBLISHED