CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family DNA polymerase

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P15436
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P15436
DPOD_YEAST
Saccharomyces cerevisiae S288C
DNA polymerase delta catalytic subunit

PDB Structure

PDB 3IAY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta
Swan, M.K., Johnson, R.E., Prakash, L., Prakash, S., Aggarwal, A.K.
Nat.Struct.Mol.Biol.