CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Cyclopropane mycolic acid synthase 1 |
Enzyme Information
| 2.1.1.79 |
Cyclopropane-fatty-acyl-phospholipid synthase.
based on mapping to UniProt P9WPB5
S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl- L-homocysteine + phospholipid cyclopropane fatty acid.
-!- Adds a methylene group across the 9,10 position of a Delta(9)- olefinic acyl chain in phosphatidylethanolamine or, more slowly, phosphatidylglycerol or phosphatidylinositol forming a cyclopropane derivative (cf. EC 2.1.1.16).
|
UniProtKB Entries (1)
| P9WPB5 |
CMAS2_MYCTU
Mycobacterium tuberculosis H37Rv
Cyclopropane mycolic acid synthase 2
|
PDB Structure
| PDB | 3HEM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Mycobacterium tuberculosis Mycolic Acid Cyclopropane Synthase CmaA2 in Complex with Dioctylamine
TO BE PUBLISHED
|