CATH Classification

Domain Context

CATH Clusters

Superfamily Galactose-binding domain-like
Functional Family Ephrin type-B receptor 2

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P54763
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P54763
EPHB2_MOUSE
Mus musculus
Ephrin type-B receptor 2

PDB Structure

PDB 3ETP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.
Goldgur, Y., Paavilainen, S., Nikolov, D., Himanen, J.P.
Acta Crystallogr.,Sect.F