CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1330 | 60s Ribosomal Protein L30; Chain: A; | |
3.30.1330.50 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
Domain Context
CATH Clusters
Superfamily | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
Functional Family | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
Enzyme Information
4.6.1.12 |
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
based on mapping to UniProt P62617
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.
|
UniProtKB Entries (1)
P62617 |
ISPF_ECOLI
Escherichia coli K-12
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
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PDB Structure
PDB | 3ELC |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem.
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