CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonucleoside hydrolase-like
Functional Family Pyrimidine-specific ribonucleoside hydrolase RihB

Enzyme Information

3.2.2.8
Ribosylpyrimidine nucleosidase.
based on mapping to UniProt P33022
A pyrimidine nucleoside + H(2)O = D-ribose + a pyrimidine base.
-!- Also hydrolyzes purine D-ribonucleosides, more slowly. -!- 2'-, 3'- and 5'-deoxynucleosides are not substrates.

UniProtKB Entries (1)

P33022
RIHB_ECOLI
Escherichia coli K-12
Pyrimidine-specific ribonucleoside hydrolase RihB

PDB Structure

PDB 3B9X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for substrate specificity in group I nucleoside hydrolases
Iovane, E., Giabbai, B., Muzzolini, L., Matafora, V., Fornili, A., Minici, C., Giannese, F., Degano, M.
Biochemistry