CATH Classification

Domain Context

CATH Clusters

Superfamily GHMP Kinase, N-terminal domain
Functional Family Ribonuclease PH

Enzyme Information

2.7.7.56
tRNA nucleotidyltransferase.
based on mapping to UniProt P9WGZ7
tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.
-!- Brings about the final exonucleolytic trimming of the 3'-terminus of tRNA precursors in Escherichia coli by a phosphorolysis, producing a mature 3'-terminus in tRNA and nucleoside diphosphate. -!- Not identical with EC 2.7.7.8.

UniProtKB Entries (1)

P9WGZ7
RNPH_MYCTU
Mycobacterium tuberculosis H37Rv
Ribonuclease PH

PDB Structure

PDB 3B4T
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis.
Antczak, A.J., Lekin, T., Segelke, B.W., Berger, J.M.
To be Published