CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Glycyl-tRNA synthetase 1

Enzyme Information

2.7.7.-
Nucleotidyltransferases.
based on mapping to UniProt P41250
6.1.1.14
Glycine--tRNA ligase.
based on mapping to UniProt P41250
ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

UniProtKB Entries (1)

P41250
GARS_HUMAN
Homo sapiens
Glycine--tRNA ligase

PDB Structure

PDB 2ZXF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis
Guo, R.T., Chong, Y.E., Guo, M., Yang, X.L.
To be Published