CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Euchromatic histone-lysine N-methyltransferase 2

Enzyme Information

2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9H9B1
2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H9B1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q9H9B1
EHMT1_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase EHMT1

PDB Structure

PDB 2RFI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural biology of human H3K9 methyltransferases
Wu, H., Min, J., Lunin, V.V., Antoshenko, T., Dombrovski, L., Zeng, H., Allali-Hassani, A., Campagna-Slater, V., Vedadi, M., Arrowsmith, C.H., Plotnikov, A.N., Schapira, M.
Plos One