CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family UDP-glucose 6-dehydrogenase

Enzyme Information

1.1.1.22
UDP-glucose 6-dehydrogenase.
based on mapping to UniProt O60701
UDP-glucose + 2 NAD(+) + H(2)O = UDP-glucuronate + 2 NADH.
-!- Also acts on UDP-2-deoxyglucose.

UniProtKB Entries (1)

O60701
UGDH_HUMAN
Homo sapiens
UDP-glucose 6-dehydrogenase

PDB Structure

PDB 2Q3E
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and mechanism of human UDP-glucose 6-dehydrogenase.
Egger, S., Chaikuad, A., Kavanagh, K.L., Oppermann, U., Nidetzky, B.
J.Biol.Chem.