CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.2140.20
Functional Family Arylamine N-acetyltransferase 1

Enzyme Information

2.3.1.5
Arylamine N-acetyltransferase.
based on mapping to UniProt P18440
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
-!- Wide specificity for aromatic amines, including serotonin; also catalyzes acetyl-transfer between arylamines without CoA.

UniProtKB Entries (1)

P18440
ARY1_HUMAN
Homo sapiens
Arylamine N-acetyltransferase 1

PDB Structure

PDB 2PQT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Basis of Substrate-binding Specificity of Human Arylamine N-Acetyltransferases.
Wu, H., Dombrovsky, L., Tempel, W., Martin, F., Loppnau, P., Goodfellow, G.H., Grant, D.M., Plotnikov, A.N.
J.Biol.Chem.