CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Ribosomal RNA small subunit methyltransferase C |
Enzyme Information
| 2.1.1.172 |
16S rRNA (guanine(1207)-N(2))-methyltransferase.
based on mapping to UniProt P39406
S-adenosyl-L-methionine + guanine(1207) in 16S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(1207) in 16S rRNA.
-!- The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA. -!- The enzyme specifically methylates guanine(1207) at N(2) in 16S rRNA. -!- Formerly EC 2.1.1.52.
|
UniProtKB Entries (1)
| P39406 |
RSMC_ECOLI
Escherichia coli K-12
Ribosomal RNA small subunit methyltransferase C
|
PDB Structure
| PDB | 2PJD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC
Nucleic Acids Res.
|