CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Phosphoadenosine phosphosulfate reductase

Enzyme Information

1.8.4.8
Phosphoadenylyl-sulfate reductase (thioredoxin).
based on mapping to UniProt P18408
Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
-!- Specific for PAPS. -!- The enzyme from Escherichia coli will use thioredoxins from other species. -!- Formerly EC 1.8.99.4.

UniProtKB Entries (1)

P18408
MET16_YEAST
Saccharomyces cerevisiae S288C
Phosphoadenosine phosphosulfate reductase

PDB Structure

PDB 2OQ2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Saccharomyces cerevisiae 3'-phosphoadenosine-5'-phosphosulfate reductase complexed with adenosine 3',5'-bisphosphate.
Yu, Z., Lemongello, D., Segel, I.H., Fisher, A.J.
Biochemistry